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While NRF1 and NRF2 are differentially regulated by KEAP1 60 , both have overlapping targets and roles in preventing liver-related diseases 61
Trial participants were randomized to tirzepatide or placebo, and primary outcomes were time to cardiovascular death or worsening HF and change in KCCQ-Clinical Summary Score (CSS) at 52 weeks
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Those clients include many major pharmaceutical companies, he said
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